Flow cytometry is a methodology that allows performing simultaneous multi-parametric analysis of single cells in solution. Flow cytometers utilize lasers as light sources to produce both scattered and fluorescent light signals. Cell populations can be characterized and/or purified based on their fluorescent or light scattering characteristics.

Protein expression on cell surface and intracellular molecules can be detected using appropriate fluorescent probes. This technology can be also applied in medium-throughput screening to study the interaction of compounds for a target of interest, for instance by competition binding.

Celtarys Ligands validated for Flow Cytometry assays

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If you want to know more about how to use fluorescent ligands to characterize receptors with pharmacological interest with this and other technologies, click on the button to download the article “Fluorescent ligands: A new method to label your GPCRs”

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