27 March 2025
Fluorescent Ligands in Fluorescence Polarization Assays

Fluorescent Ligands in Fluorescence Polarization Assays: A Game-Changer for GPCR Drug Discovery

The development of new therapeutics depends on the ability to identify compounds that interact with specific molecular targets involved in disease pathways. Target-based screening has become […]
4 March 2025
Advantages of fluorescent probes in GPCR assays

Advantages of Fluorescent Probes in GPCR Assays

The field of drug discovery faces a critical challenge: despite their vast therapeutic potential, many G Protein-Coupled Receptors (GPCRs) remain unexplored. These receptors play a fundamental […]
21 February 2025
radioligands vs fluorescent ligands

Radioligands vs. Fluorescent Ligands: Binding Assays

Studying receptor-ligand interaction is a crucial approach in drug discovery and biomedical research. Radioligands have been the gold standard for binding assays since their first use […]
16 January 2024

Celtarys develops a new FRET based assay in collaboration with CiQUS and CiMUS

We are very proud to present our last paper in collaboration with the Institute of Neuroscience of the Universitat de Barcelona, the CiQUS – Center for Research in […]
18 October 2023

Celtarys expands its catalogue of receptor ligands with the first commercially available red-emitting fluorescent σ1/σ2 ligands

Sigma (σ) receptor subtypes, σ1 and σ2, are targets of wide pharmaceutical interest. σ1 receptor ligands are under evaluation in clinical trials for the treatment of diseases such as […]
11 September 2023

Celtarys and G.CLIPS join forces to revolutionize transmembrane proteins characterization in drug discovery. 

A major bottleneck in drug discovery, particularly when targeting transmembrane proteins such as G-coupled receptor proteins (GPCRs), is the challenge of replicating in vitro the precise microenvironment conditions […]
19 July 2023

Celtarys extends its chemical conjugation technology to the development of new fluorescent ligands for E3 Ubiquitin ligases

Traditional pharmacological mechanisms leave a significant part of the genome ‘undruggable’, due to the inability to induce or block their activity using agonists and antagonists. Thanks […]
13 July 2023

CELTARY & NANOTEMPER-Discovery partnership to enhance performance in GPCR characterization

Celtarys expands its presence in the GPCR field, developing new applications in collaboration agreement with Nanotemper, a company devoted to the development of innovative instruments for […]
10 July 2023

Transform your biosensor into an innovative technology

The fabrication of a particular device depends heavily on the immobilization of the biosensing element (a probe such as an antibody, aptamer, etc.) onto the transducer […]