Functional activity data of GPCRs (G protein-coupled receptors) are crucial in drug discovery programs for monitoring therapeutic effects and potential off-target side effects. A reliable and efficient assay for this purpose uses the non-hydrolysable GTP derivative, GTPγS, which enables the detection of G protein activation upon ligand binding. Fluorescent GTPγS offers a significant advantage over radioactive [³⁵S]GTPγS by providing the same sensitivity and robustness while allowing assays to be conducted using conventional lab equipment.
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CELT-505 fluorescent GTPγS – Green Emission Spectrum (503/509)
For research use only50 µg vial that allows to prepare 435 mL of 100 nM working solution. Working concentration might differ among assay designs.
199,00€ View more -
CELT-503 fluorescent GTPγS – Red Emission Spectrum (589/616)
For research use only50 µg vial that allows to prepare 390 mL of 100 nM working solution. Working concentration might differ among assay designs.
199,00€ View more
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