Identifying new E3 Ubiquitin ligase ligands for new PROTACs design is a key element that can improve selective proteasomal-dependent degradation of proteins of interest involved in many pathological processes such as cancer, chronic anaemia, and ischemia.
Our fluorescent probes for VHL and CRBN E3 ligase are powerful tools both for compound screening for new E3ligase ligands and for PROTACs analysis, suitable for in vitro microscopy, binding assays such as TR-FRET competition assays.
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CELT-077 CRBN E3 ligase fluorescent ligand (589/616)
For research use only50 µg vial that allows to prepare 231 mL of 200 nM working solution.
250,00€ View more
Working concentration might differ among assay designs -
CELT-081 CRBN E3 ligase fluorescent ligand (646/662)
For research use only50 µg vial that allows to prepare 197 mL of 200 nM working solution.
250,00€ View more
Working concentration might differ among assay designs -
CELT-504 VHL E3 ligase fluorescent ligand (564/570)
For research use only50 µg vial that allows to prepare 235 mL of 200 nM working solution.
250,00€ View more
Working concentration might differ among assay designs -
CELT-050 VHL E3 ligase fluorescent ligand (646/662)
For research use only50 µg vial that allows to prepare 166 mL of 200 nM working solution.
250,00€ View more
Working concentration might differ among assay designs
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