Our Oxytocin receptor fluorescent and/or fluorogenic ligands have been used in a variety of imaging applications, including TR-FRET and confocal microscopy.
CELT-501 and CELT-502 have been developed by the team of Dominique Bonnet from the Laboratory for Therapeutic Innovation (University of Strasbourg) and have been licensed to Celtarys for commercialization.
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Our potent hOT receptor fluorescent agonist shows high affinity for hOT receptor (Ki =0,54 nM in radioligand binding assay). It allows to perform cell visualization in fluorescence microscopy, confocal microscopy, high content system experiments and TR-FRET experiments. It is potentially suitable for other fluorescence-based assays.
Our potent and selective hOT receptor fluorescent antagonist shows high affinity for hOT receptor (Kd =1,59 nMin TR-FRET saturation binding assay). It allows to perform cell visualization in fluorescence microscopy, confocal microscopy, high content system experiments and TR-FRET experiments. It is potentially suitable for other fluorescence-based assays.