Our potent CELT-050 VHL E3 ligase fluorescent ligand is a tracer for VHL E3 ligases binding assays, designed to perform affinity binding curves to VHL protein using TR-FRET homogenous technology.
Von Hippel–Lindau protein (VHL) is the substrate recognition subunit of an E3 ligase recruited by bifunctional Proteolysis-targeting chimeras (PROTACs) to induce ubiquitination and subsequent proteasomal degradation of a targeted protein.
CELT-050 VHL E3 ligase fluorescent ligand (646/662)
10 µg vial that allows to prepare 33 mL of 200 nM working solution.
Working concentration might differ among assay designs
250,00€